Long-Term Safety of Pirtobrutinib in Participants From Study J2N-MC-JZNJ With Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma or Non-Hodgkin Lymphoma

Status: Recruiting
Location: See all (6) locations...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 2
SUMMARY

The purpose of this study is to find out more about the long-term safety of pirtobrutinib in participants with previously treated types of blood cancer. Participants must have chronic lymphocytic leukemia, small lymphocytic lymphoma, or non-Hodgkins lymphoma. The study is open to those who completed the original study - J2N-MC-JZNJ (NCT04849416) and continue to benefit from treatment. Treatment will be given every 12 weeks and this study is expected to last about 5 years.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Currently enrolled and active in the originator study, JZNJ. A participant is considered active in the study if they are receiving study intervention

• Agree to comply with contraception requirements. Contraceptive use by participants should be consistent with local regulations regarding the methods of contraception for those participating in clinical studies

Locations
Other Locations
China
Beijing Cancer hospital
NOT_YET_RECRUITING
Beijing
Sun Yat-sen University Cancer Center
NOT_YET_RECRUITING
Guangzhou
Harbin Medical University Cancer Hospital
NOT_YET_RECRUITING
Harbin
Shanghai East Hospital
ACTIVE_NOT_RECRUITING
Shanghai
Blood Institute of the Chinese Academy of Medical science
NOT_YET_RECRUITING
Tianjin
Union Hospital Tongji Medical College Huazhong University of Science and Technology
RECRUITING
Wuhan
Contact Information
Primary
Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or
LillyTrials@Lilly.com
1-317-615-4559
Backup
Physicians interested in becoming principal investigators please contact
clinical_inquiry_hub@lilly.com
Time Frame
Start Date: 2025-08-07
Estimated Completion Date: 2030-05
Participants
Target number of participants: 13
Treatments
Experimental: Pirtobrutinib
Pirtobrutinib administered orally.
Sponsors
Leads: Eli Lilly and Company

This content was sourced from clinicaltrials.gov